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Biodegradable Semi-Rigid Mitral Valve Annuloplasty Ring Designed for Children
https://doi.org/10.57457/0002000082
https://doi.org/10.57457/0002000082a14055d8-f9ef-4260-9363-1b7019ee6890
| 名前 / ファイル | ライセンス | アクション |
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本文 (814 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2024-01-30 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Biodegradable Semi-Rigid Mitral Valve Annuloplasty Ring Designed for Children | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | mitral valve | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | annuloplasty ring | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | biodegradable polymer | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | children | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| ID登録 | ||||||||||||||
| ID登録 | 10.57457/0002000082 | |||||||||||||
| ID登録タイプ | JaLC | |||||||||||||
| 著者 |
安藤 誠
× 安藤 誠
× 西野 貴子
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| 著者（英） | ||||||||||||||
| 姓名 | Makoto Ando | |||||||||||||
| 言語 | en | |||||||||||||
| 著者（英） | ||||||||||||||
| 姓名 | Takako Nishino | |||||||||||||
| 言語 | en | |||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Descriptive information has indicated unsatisfactory outcomes associated with mitral valve plasty in the case of pediatric patients. Conversely, favorable outcomes have been consistently reported in adult cases, primarily attributed to the feasibility of prosthetic annuloplasty rings. Due to this notable distinction, we aimed to address the specific needs of small children by developing a semi-rigid annuloplasty ring for the mitral valve, employing biodegradable polymers. The expectation is that this approach would involve the gradual degradation and absorption of the developed semi-rigid annuloplasty ring, coinciding with the remodeling of the mitral annulus. The inner support medium was crafted from sutures composed of a blend of poly L-lactic acid and poly ɛ-caprolactone copolymer, mixed at a molar ratio of 3:1. Subsequently, this material was bundled together and coiled around a saddle-shaped mold rod. Following heat processing, a reinforced saddle-shaped rod with a diameter of 0.6mm was successfully created. The external cuff utilized a blade weaving technique made of polyglycolic acid, facilitating the smooth insertion of needles. A blade material was woven using 16 sets of polyglycolic acid sutures (size 50D), resulting in an internal diameter of 2mm and an area density of 0.55mg/mm³. The internal rod was inserted within the polyglycolic acid blade, and both ends were subjected to heat processing at a temperature of 230°C for 10 seconds to prevent fraying. This device holds the potential to offer a solution for enhancing the outcomes of pediatric mitral valve plasty, and address the current challenges associated with unsatisfactory results in this patient population. Additionally, its applicability to adult patients could potentially eliminate the requirement for lifelong anticoagulation therapy. | |||||||||||||
| 言語 | en | |||||||||||||
| 書誌情報 |
巻 48, 号 2, p. 65-69, 発行日 2023-12 |
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| 出版者 | ||||||||||||||
| 出版者 | 金沢医科大学医学会 | |||||||||||||
| 言語 | ja | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 2436-6994 | |||||||||||||
| 著者版フラグ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
