{"_buckets": {"deposit": "784964e7-a75a-4d6b-b56c-a9eabe79efea"}, "_deposit": {"created_by": 5, "id": "2000127", "owner": "5", "owners": [5], "pid": {"revision_id": 0, "type": "depid", "value": "2000127"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-med.repo.nii.ac.jp:02000127", "sets": ["1711524893657"]}, "author_link": [], "control_number": "2000127", "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2024-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "37", "bibliographicPageStart": "35", "bibliographicVolumeNumber": "49"}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "A 12-year-old Japanese boy presented with epigastric pain and swelling of the neck. Biopsy of the cervical lymph node and the bone marrow showed diffuse proliferation of lymphoblastic cells with precursor T-cell immunophenotypes. The patient was diagnosed with stage IV T-lymphoblastic lymphoma (T-LBL) and complete remission was successfully achieved after induction chemotherapy without any adverse events. At 10 months after diagnosis, he presented with an abrupt onset of transfusion-refractory thrombocytopenia during maintenance therapy. Bone marrow examinations revealed hypoplastic marrow with phagocytosis of the blood cells by multinucleated giant cells with foamy cytoplasm and a diagnosis of hemophagocytic lymphohistiocytosis (HLH) was confirmed. No evidence of T-LBL relapse was found by positron emission tomography. He progressed to severe bone marrow failure and underwent allogeneic stem cell transplantation (SCT) from his human leukocyte antigen (HLA)-matched brother. He achieved complete remission with partial hematological recovery. Unfortunately, the patient died from relapsed T-LBL at 6 months after SCT. The onset of HLH during childhood cancer therapy is extremely rare, but these conditions often develop chemoresistance resulting in a lethal outcome. Therefore, they may require more intensive myeloablative therapy with stem cell rescue.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10001_full_name_3": {"attribute_name": "著者(英)", "attribute_value_mlt": [{"names": [{"name": "Naoki Okada", "nameLang": "en"}]}, {"names": [{"name": "Reiko Fujisawa", "nameLang": "en"}]}, {"names": [{"name": "Yutaka Saikawa", "nameLang": "en"}]}, {"names": [{"name": "Hitoshi Sato", "nameLang": "en"}]}]}, "item_10001_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.57457/0002000127", "subitem_identifier_reg_type": "JaLC"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "金沢医科大学医学会", "subitem_publisher_language": "ja"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2436-6994", "subitem_source_identifier_type": "EISSN"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "岡田 直樹", "creatorNameLang": "ja"}, {"creatorName": "オカダ ナオキ", "creatorNameLang": "ja-Kana"}]}, {"creatorNames": [{"creatorName": "藤澤 麗子", "creatorNameLang": "ja"}, {"creatorName": "フジサワ レイコ", "creatorNameLang": "ja-Kana"}]}, {"creatorNames": [{"creatorName": "犀川 太", "creatorNameLang": "ja"}, {"creatorName": "サイカワ ユタカ", "creatorNameLang": "ja-Kana"}]}, {"creatorNames": [{"creatorName": "佐藤 仁志", "creatorNameLang": "ja"}, {"creatorName": "サトウ ヒトシ", "creatorNameLang": "ja-Kana"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2024-04-01"}], "displaytype": "detail", "download_preview_message": "", "fileDate": [{"fileDateType": "Issued", "fileDateValue": "2024-04-01"}], "file_order": 0, "filename": "49(1)35-37.pdf", "filesize": [{"value": "1.7 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "application/pdf", "size": 1700000.0, "url": {"label": "本文", "url": "https://kanazawa-med.repo.nii.ac.jp/record/2000127/files/49(1)35-37.pdf"}, "version_id": "e09c4127-817a-41da-833b-ecb73254b08a"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "hemophagocytosis", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lymphohistiocytosis", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "T-lymphoblastic lymphoma", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Hemophagocytic Lymphohistiocytosis during the Treatment of T-lymphoblastic Lymphoma", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Hemophagocytic Lymphohistiocytosis during the Treatment of T-lymphoblastic Lymphoma", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "5", "path": ["1711524893657"], "permalink_uri": "https://doi.org/10.57457/0002000127", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2024-03-29"}, "publish_date": "2024-03-29", "publish_status": "0", "recid": "2000127", "relation": {}, "relation_version_is_last": true, "title": ["Hemophagocytic Lymphohistiocytosis during the Treatment of T-lymphoblastic Lymphoma"], "weko_shared_id": -1}
Hemophagocytic Lymphohistiocytosis during the Treatment of T-lymphoblastic Lymphoma
https://doi.org/10.57457/0002000127
https://doi.org/10.57457/0002000127